| 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline; papaverine | |
| Links: | 📖 PubMed, 📖Houben-Weyl, 2. Band (Papaverin); p. 683, |
| MeSH: | Enzyme Inhibitors |
| CAS RN: | [58-74-2] |
| Formula: | C20H21NO4; 339.39 g/mol |
| InChiKey: | XQYZDYMELSJDRZ-UHFFFAOYSA-N |
| SMILES: | COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC |
| Pharmaceutical use: | antianginal; antiasthmatic; anticholinergic; antispasmodic; myorelaxant |
| Toxicology (LD50): | 1 000 mg/Kg (frog, sc); 32.0 mg/Kg(mouse, iv); 2 500 mg/Kg(mouse, or); 500 mg/Kg(mouse, sc); 150 mg/Kg(pigeon, sc); 250 mg/Kg(rabbit, sc); 62.0 mg/Kg(rat, ip); 745 mg/Kg(rat, or) |
| Melting point: | 147 °C |
| Log10 partition octanol / water: | 2.95 |
| 1g dissolves in: 3.45g aniline; 12.50g pyridine; 100.00g piperidine; 193.05g tetrachloromethane; 250.00g diethylamine; 263.16g diethyl ether | |